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 BioStatistical Blog
 1. Statistic’s Dirty Little Secret
 1.A Another view on testing by Peter Flom, PhD
 1.B Am I a nattering nabob of negativism?
 2. Why do we compute pvalues?
 3. Meaningful ways to determine the adequacy of a treatment effect when you have an intuitive knowledge of the dependent variable
 4. Meaningful ways to determine the adequacy of a treatment effect when you lack an intuitive knowledge of the dependent variable
 5. Accepting the null hypothesis
 6. ‘Lies, Damned Lies, and Statistics’ part 1, and Analysis Plans, an essential tool
 7. Assumptions of Statistical Tests
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Stat comments and Questions
 Allen Fleishman on 22. A question on QoL, Percentage Change from Baseline, and CompassionateUsage Protocols
 Kate on 22. A question on QoL, Percentage Change from Baseline, and CompassionateUsage Protocols
 Allen Fleishman on 24. Simple, but SimpleMinded
 Victor Levenson on 24. Simple, but SimpleMinded
 Allen Fleishman on 24. Simple, but SimpleMinded
 Victor Levenson on 24. Simple, but SimpleMinded
 Allen Fleishman on 12. Significant pvalues in small samples
 Merm on 12. Significant pvalues in small samples
 Allen Fleishman on 12. Significant pvalues in small samples
 Phil Assheton on 12. Significant pvalues in small samples
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Category Archives: Statistical
1. Statistic’s Dirty Little Secret
I can’t believe schools are still teaching kids about the null hypothesis. I remember reading a big study that conclusively disproved it years ago. *** To most scientists, the endpoint of a research study is achieving the mystical ‘p < 0.05’, … Continue reading
2. Why do we compute pvalues?
In my previous blog I said that the pvalue, which test the null hypothesis, is a near meaningless concept. This was based on: In nature, the likelihood that the difference between two different treatments will be exactly any number (e.g., … Continue reading
3. Meaningful ways to determine the adequacy of a treatment effect when you have an intuitive knowledge of the dependent variable
“A theory has only the alternative of being wrong. A model has a third possibility – it might be right but irrelevant.” Manfred Eigen In my last stats course I was amazed to hear my teacher announce that If we … Continue reading
6. ‘Lies, Damned Lies, and Statistics’ part 1, and Analysis Plans, an essential tool
Lies, Damn Lies, and Statistics Let me start this blog with one of my pet peeves. I abhor the quote ‘Lies, Damn Lies, and Statistics’. For me, a statistician, it has as much truth as saying that ‘the earth is … Continue reading
8. What is a Power Analysis?
People who haven’t the time to do things ‘perfectly’, always have time to do them over. Measure once, cut twice. Measure twice, cut once. ‘My god, you’ve conclusively proven it. Time equals Money.’ *** Cost for Failure Every CEO I’ve … Continue reading
10. Parametric or nonparametric analysis – Why one is almost useless
… ‘If you lost your watch in that dark alley, why are we looking here?’ ‘Well, <hic> there’s light here.’ (old chestnut) *** In my last blog, I stated that we should avoid dichotomizing as it throws away a lot … Continue reading
BioStatistical Blog
I have retired from consulting. However I will post blogs on statistics when I see interesting materials to comment on. Allen I. Fleishman, PhD, PStat® Did you hear the joke about statisticians? … Probably “Professor, do I look like a … Continue reading →